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Chem Impex
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Product Information

Product Name
Fmoc-O-phospho-L-tyrosine
Brand Name
Chem Impex
Product Number
03747
CAS
147762-53-6
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
10917854
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-phosphonooxyphenyl)propanoic acid
InChI Key
AMXUJIHSMANWDW-QFIPXVFZSA-N
SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC@@H(CC4=CC=C(C=C4)OP(=O)(O)O)C(=O)O

Description

Fmoc-O-phospho-L-tyrosine is widely utilized in research focused on:

Peptide Synthesis: This compound is a key building block in the synthesis of phosphorylated peptides, which are crucial for studying protein interactions and signaling pathways.

Drug Development: Its ability to mimic phosphorylated amino acids makes it valuable in the design of drugs targeting specific protein functions, particularly in cancer research.

Bioconjugation: Fmoc-O-phospho-L-tyrosine can be used to create conjugates with biomolecules, enhancing the delivery and efficacy of therapeutic agents.

Analytical Chemistry: Researchers utilize this compound in assays to detect and quantify phosphorylation states of proteins, aiding in the understanding of cellular processes.

Biotechnology: It plays a significant role in the development of biosensors that monitor cellular responses, providing insights into metabolic and signaling pathways.

References Data Source From Pubchem

Peptide and Protein Emulsifiers

Publication Name: Peptide Bionanomaterials
Publication Date: 2023
DOI: 10.1007/978-3-031-29360-3_13

A General Method to Prepare Peptide-Based Supramolecular Hydrogels

Publication Name: Methods in Molecular Biology
Publication Date: 2018
DOI: 10.1007/978-1-4939-7811-3_9

Colorimetric Enzyme Sensing Assays via In Situ Synthesis of Gold Nanoparticles

Publication Name: Journal of Cluster Science
Publication Date: 2013-07-18
DOI: 10.1007/s10876-013-0606-z

Cerium oxide nanoparticle-mediated self-assembly of hybrid supramolecular hydrogels

Publication Name: Chemical communications (Cambridge, England)
Publication Date: 2012-08-18
DOI: 10.1039/c2cc33351a

Hydrogen-Bonding Interactions Induced by Phosphorylation Influence the Local Conformation of Phosphopeptides

Publication Name: International Journal of Peptide Research and Therapeutics
Publication Date: 2010-04-04
DOI: 10.1007/s10989-010-9207-y