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Chem Impex
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Product Information

Product Name
Boc-O-tert-butyl-L-tyrosine
Brand Name
Chem Impex
Product Number
01392
CAS
47375-34-8
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
7017901
IUPAC Name
(2S)-2-(2-methylpropan-2-yl)oxycarbonylamino-3-4-(2-methylpropan-2-yl)oxyphenylpropanoic acid
InChI Key
ZEQLLMOXFVKKCN-AWEZNQCLSA-N
SMILES
CC(C)(C)OC1=CC=C(C=C1)CC@@H(C(=O)O)NC(=O)OC(C)(C)C

Application

Boc-O-tert-butyl-L-tyrosine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for selective reactions without affecting the amino acid's functionality. This is particularly beneficial in pharmaceutical development where precise modifications are essential.

Drug Development: Its role in modifying drug candidates enhances their stability and bioavailability. Researchers can use it to create prodrugs that improve therapeutic efficacy, especially in cancer treatments.

Bioconjugation: The compound is useful in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules. This application is crucial in creating targeted drug delivery systems and diagnostic tools.

Research in Neuroscience: Boc-O-tert-butyl-L-tyrosine can be used in studies investigating neurotransmitter pathways, aiding in the development of treatments for neurological disorders.

Custom Synthesis: Its versatility allows chemists to tailor it for specific applications, making it a valuable tool in custom synthesis projects across various fields, including materials science and biotechnology.

References Data Source From Pubchem

N-carboxyacyl and N-α-aminoacyl derivatives of aminoaldehydes as shared substrates of plant aldehyde dehydrogenases 10 and 7

Publication Name: Amino Acids
Publication Date: 2024-08-29
DOI: 10.1007/s00726-024-03415-4

Chemoproteomic Profiling of Adenylation Domain Functions in Gramicidin S-Producing Non-ribosomal Peptide Synthetases

Publication Name: Non-Ribosomal Peptide Biosynthesis and Engineering
Publication Date: 2023
DOI: 10.1007/978-1-0716-3214-7_4

Serine/Threonine Ligation and Cysteine/Penicillamine Ligation

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2022-06-28
DOI: 10.1007/978-1-0716-2489-0_3

Synthesis of P- and S-Stereogenic Compounds via Enantioselective C–H Functionalization

Publication Name: Synthesis
Publication Date: 2022-05-12
DOI: 10.1055/a-1802-6793

Tyrosinyl-amantadine: A New Amantadine Derivative With an Ameliorative Effect in a 6-OHDA Experimental Model of Parkinson’s Disease in Rats

Publication Name: Journal of molecular neuroscience : MN
Publication Date: 2022-01-28
DOI: 10.1007/s12031-021-01964-x