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Product Information

Product Name
O-tert-Butyl-L-tyrosine
Brand Name
Chem Impex
Product Number
00435
CAS
18822-59-8
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
7408092
IUPAC Name
(2S)-2-amino-3-4-(2-methylpropan-2-yl)oxyphenylpropanoic acid
InChI Key
SNZIFNXFAFKRKT-NSHDSACASA-N
SMILES
CC(C)(C)OC1=CC=C(C=C1)CC@@H(C(=O)O)N

Application

O-tert-Butyl-L-tyrosine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of therapeutic agents and research tools in biochemistry.

Drug Development: Its unique properties allow for the modification of drug candidates, enhancing their stability and bioavailability, which is crucial in pharmaceutical formulations.

Protein Engineering: Researchers use it to introduce specific functionalities into proteins, aiding in the design of novel enzymes and therapeutic proteins with improved characteristics.

Biochemical Assays: O-tert-Butyl-L-tyrosine is employed in various assays to study enzyme activity and protein interactions, providing insights into metabolic pathways and disease mechanisms.

Neuroscience Research: It plays a role in studying neurotransmitter systems, particularly in understanding the effects of tyrosine derivatives on brain function and behavior.

References Data Source From Pubchem

An evolved pyrrolysyl-tRNA synthetase with polysubstrate specificity expands the toolbox for engineering enzymes with incorporation of noncanonical amino acids

Publication Name: Bioresources and Bioprocessing
Publication Date: 2023-12-11
DOI: 10.1186/s40643-023-00712-w

Recent advancements in enzyme engineering via site-specific incorporation of unnatural amino acids

Publication Name: World Journal of Microbiology and Biotechnology
Publication Date: 2021-11-06
DOI: 10.1007/s11274-021-03177-1

Incorporation of Azide and Alkyne Functionalities into Peptides

Publication Name: Science of Synthesis
Publication Date: 2021

Expanding the enzyme universe with genetically encoded unnatural amino acids

Publication Name: Nature Catalysis
Publication Date: 2020-01-06
DOI: 10.1038/s41929-019-0410-8

Deaminative Bromination (Bromodediazoniation) of Chiral α-Amino Acids

Publication Name: Science of Synthesis
Publication Date: 2007