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Sku CI00116_5_G
Chem Impex
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Product Information

Product Name
3,5-Diiodo-L-tyrosine dihydrate
Brand Name
Chem Impex
Product Number
00116
CAS
18835-59-1
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
2724330
IUPAC Name
(2S)-2-amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid;dihydrate
InChI Key
YWAGQOOMOOUEGY-KLXURFKVSA-N
SMILES
C1=C(C=C(C(=C1I)O)I)CC@@H(C(=O)O)N.O.O

Application

3,5-Diiodo-L-tyrosine dihydrate is widely utilized in research focused on:

Thyroid Hormone Research: This compound is a key player in studying thyroid hormone synthesis and metabolism, helping researchers understand disorders like hypothyroidism and hyperthyroidism.

Radiopharmaceuticals: It serves as a precursor in the production of iodine-125 labeled compounds, which are essential in diagnostic imaging techniques, particularly in nuclear medicine.

Biochemical Studies: The compound is used in various biochemical assays to investigate the role of iodinated tyrosines in protein function and enzyme activity, providing insights into metabolic pathways.

Drug Development: Its unique properties make it a candidate for developing new therapeutic agents targeting thyroid-related diseases, offering potential advantages over traditional treatments.

Nutrition Research: 3,5-Diiodo-L-tyrosine dihydrate is studied for its effects on dietary iodine intake and its implications for public health, particularly in regions with iodine deficiency.

References Data Source From Pubchem

5-Bromouracil-gracillin (5BrU-G) complex: an APOBEC3-activated therapeutic strategy exploiting cancer-specific enzymatic activity for selective cytotoxicity

Publication Name: Medical oncology (Northwood, London, England)
Publication Date: 2025-05-08
DOI: 10.1007/s12032-025-02745-x

Bestimmung der Jodzahl von Phospholipiden

Publication Name: Fresenius' Zeitschrift für analytische Chemie
Publication Date: 1955
DOI: 10.1007/bf00438087

Eine Methode zur direkten Messung von radioaktivem Jod in hydrolysierten Schilddrüsenfraktionen

Publication Name: Fresenius' Zeitschrift für analytische Chemie
Publication Date: 1955
DOI: 10.1007/bf00438088

Zur Bestimmung von 3,5-Dijodtyrosin

Publication Name: Fresenius' Zeitschrift für analytische Chemie
Publication Date: 1955
DOI: 10.1007/bf00438089