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Sku CI30782_100_MG
Chem Impex
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Product Information

Product Name
Na-Fmoc-Nin-methyl-L-tryptophan
Brand Name
Chem Impex
Product Number
30782
CAS
1334509-86-2
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
53832785
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-methylindol-3-yl)propanoic acid
InChI Key
GDPXIUSEXJJUGT-DEOSSOPVSA-N
SMILES
CN1C=C(C2=CC=CC=C21)CC@@H(C(=O)O)NC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35

Description

Na-Fmoc-Nin-methyl-L-tryptophan is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides with high purity and yield.

Drug Development: It plays a significant role in the pharmaceutical industry for developing novel therapeutic peptides, particularly those targeting neurological disorders due to its structural similarity to neurotransmitters.

Bioconjugation: This chemical is used in bioconjugation processes, enabling the attachment of peptides to various biomolecules, which is essential for creating targeted drug delivery systems.

Research in Neuroscience: Its unique properties make it valuable in neuroscience research, particularly in studying the effects of tryptophan derivatives on serotonin pathways and mood regulation.

Fluorescent Labeling: The Fmoc group allows for easy incorporation into fluorescently labeled peptides, facilitating the study of protein interactions in live cells.

References Data Source From Pubchem

Radical Additions to Aromatic Residues in Peptides Facilitate Unexpected Side Chain and Backbone Losses

Publication Name: Journal of The American Society for Mass Spectrometry
Publication Date: 2014-02-01
DOI: 10.1007/s13361-013-0810-y