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Sku CI12395_1_G
Chem Impex
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Product Information

Product Name
Na-Fmoc-D-tryptophan N-hydroxysuccinimide ester
Brand Name
Chem Impex
Product Number
12395
CAS
174080-12-7
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
56777157
IUPAC Name
(2,5-dioxopyrrolidin-1-yl) (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1H-indol-3-yl)propanoate
InChI Key
WWQYTEPUEUNBOM-AREMUKBSSA-N
SMILES
C1CC(=O)N(C1=O)OC(=O)C@@H(CC2=CNC3=CC=CC=C32)NC(=O)OCC4C5=CC=CC=C5C6=CC=CC=C46

Description

Na-Fmoc-D-tryptophan N-hydroxysuccinimide ester is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly for creating complex sequences that include D-tryptophan. Its use enhances the efficiency of solid-phase peptide synthesis, allowing for the production of high-purity peptides.

Drug Development: In pharmaceutical research, it is employed to develop novel drug candidates that target specific biological pathways. Its ability to modify the structure of peptides can lead to improved pharmacokinetic properties.

Bioconjugation: The N-hydroxysuccinimide ester functionality allows for easy conjugation with various biomolecules, facilitating the creation of targeted drug delivery systems and diagnostic agents in biomedicine.

Research in Neuroscience: This compound is used in studies related to neurotransmitter pathways, particularly those involving tryptophan derivatives, which are crucial for understanding mood regulation and mental health.

Protein Engineering: It plays a role in modifying proteins to enhance their stability and activity, making it valuable in the development of enzyme inhibitors and therapeutic proteins.