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Sku CI02484_25_G
Chem Impex
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Product Information

Product Name
Na-Fmoc-Nin-Boc-D-tryptophan
Brand Name
Chem Impex
Product Number
02484
CAS
163619-04-3
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
16213150
IUPAC Name
(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-1-(2-methylpropan-2-yl)oxycarbonylindol-3-ylpropanoic acid
InChI Key
ADOHASQZJSJZBT-AREMUKBSSA-N
SMILES
CC(C)(C)OC(=O)N1C=C(C2=CC=CC=C21)CC@H(C(=O)O)NC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35

Description

Na-Fmoc-Nin-Boc-D-tryptophan is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing researchers to create complex peptide chains with high purity and yield.

Drug Development: It is used in the development of pharmaceutical compounds, especially those targeting neurological disorders, by facilitating the incorporation of tryptophan derivatives into drug candidates.

Bioconjugation: The chemical is valuable in bioconjugation processes, where it helps attach biomolecules to other entities, enhancing the specificity and effectiveness of therapeutic agents.

Protein Engineering: Researchers utilize it for modifying proteins, improving their stability and functionality, which is crucial in the production of therapeutic proteins and enzymes.

Research in Neuroscience: Its application in neuroscience research is significant, as it aids in studying the role of tryptophan in serotonin production, impacting mood and behavior studies.

References Data Source From Pubchem

Impact of stereochemical replacement on activity and selectivity of membrane-active antibacterial and antifungal cyclic peptides

Publication Name: npj Antimicrobials and Resistance
Publication Date: 2025-06-17
DOI: 10.1038/s44259-025-00121-3

Rapid clearance of achiral small-molecule drugs using de novo-designed proteins and their cyclic and mirror-image variants

Publication Name: Nature Biomedical Engineering
Publication Date: 2025-05-29
DOI: 10.1038/s41551-025-01404-w

Protease Specificity Profiling Using Synthetic Combinatorial Peptide Libraries and Mass Spectrometry

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2025
DOI: 10.1007/978-1-0716-4578-9_8

Building Blocks for the Screening of Histone Deacetylase Inhibitors Using μSPOT

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2025
DOI: 10.1007/978-1-0716-4578-9_11

Accurate de novo design of heterochiral protein–protein interactions

Publication Name: Cell Research
Publication Date: 2024-08-14
DOI: 10.1038/s41422-024-01014-2