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Sku CI01954_1_KG
Chem Impex
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Product Information

Product Name
Na-Fmoc-Nin-Boc-L-tryptophan
Brand Name
Chem Impex
Product Number
01954
CAS
143824-78-6
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
9849766
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-1-(2-methylpropan-2-yl)oxycarbonylindol-3-ylpropanoic acid
InChI Key
ADOHASQZJSJZBT-SANMLTNESA-N
SMILES
CC(C)(C)OC(=O)N1C=C(C2=CC=CC=C21)CC@@H(C(=O)O)NC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35

Description

Na-Fmoc-Nin-Boc-L-tryptophan is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity and yield.

Drug Development: It plays a significant role in pharmaceutical research, particularly in the development of peptide-based drugs, which can offer targeted therapeutic effects with fewer side effects compared to traditional small molecules.

Bioconjugation: The compound is used in bioconjugation techniques, facilitating the attachment of peptides to other biomolecules, such as antibodies or nanoparticles, enhancing drug delivery systems.

Research in Neuroscience: It is valuable in studies related to neurotransmitter pathways, particularly due to tryptophan's role as a precursor to serotonin, aiding in the understanding of mood disorders.

Protein Engineering: This chemical is instrumental in the design of modified proteins, allowing researchers to explore structure-function relationships and develop proteins with enhanced stability or activity.

References Data Source From Pubchem

A novel peptide-compound conjugate alleviates endotoxin-induced inflammation via NF-κB/MAPK modulation

Publication Name: Journal of molecular medicine (Berlin, Germany)
Publication Date: 2025-12-23
DOI: 10.1007/s00109-025-02608-y

Novel cyclic heptapeptides as potential therapeutics against methicillin-resistant Staphylococcus aureus infections

Publication Name: Naunyn-Schmiedeberg's Archives of Pharmacology
Publication Date: 2025-12-08
DOI: 10.1007/s00210-025-04863-9

Protolytic properties and biological activity of spinorphin and its butyric acid derivatives in aqueous solution

Publication Name: Amino Acids
Publication Date: 2025-09-18
DOI: 10.1007/s00726-025-03481-2

Urinary bioorthogonal reporters for the monitoring of the efficacy of chemotherapy for lung cancer and of associated kidney injury

Publication Name: Nature Biomedical Engineering
Publication Date: 2025-01-29
DOI: 10.1038/s41551-024-01340-1

Synthesis of Polymyxin-Inspired Peptidomimetics

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2025
DOI: 10.1007/978-1-0716-4562-8_22