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Product Information

Product Name
Fmoc-L-threonine
Brand Name
Chem Impex
Product Number
02458
CAS
73731-37-0
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
6992530
IUPAC Name
(2S,3R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxybutanoic acid
InChI Key
OYULCCKKLJPNPU-DIFFPNOSSA-N
SMILES
CC@H(C@@H(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13)O

Application

Fmoc-L-threonine is widely utilized in research focused on

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides. Its protective Fmoc group allows for selective deprotection, facilitating the incorporation of threonine into peptide chains, which is crucial for developing therapeutic peptides.

Biotechnology: In the field of biotechnology, Fmoc-L-threonine is used in the production of recombinant proteins. Its incorporation can enhance the stability and functionality of proteins, making it valuable for drug development and enzyme engineering.

Research in Drug Design: Researchers utilize this compound to study interactions between peptides and receptors. Its unique structure aids in understanding how modifications can influence biological activity, which is essential for designing new drugs.

Analytical Chemistry: Fmoc-L-threonine is employed in analytical methods such as chromatography. Its distinct properties help in the separation and identification of amino acids and peptides, improving the accuracy of analytical results.

Food Industry Applications: This compound is also explored for its potential in food science, particularly in the development of functional foods that may enhance nutritional profiles through the incorporation of specific amino acids.

References Data Source From Pubchem

Thiazole Synthesis by Thionation of C=O to C=S

Publication Name: Lawesson’s Reagent in Heterocycle Synthesis
Publication Date: 2021-09-11
DOI: 10.1007/978-981-16-4655-3_3

Screening One-Bead-One-Compound Peptide Libraries for Optimal Kinase Substrates

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2016
DOI: 10.1007/978-1-4939-3073-9_13

Assessing the Efficacy of Mdm2/Mdm4-Inhibiting Stapled Peptides Using Cellular Thermal Shift Assays

Publication Name: Scientific Reports
Publication Date: 2015-07-10
DOI: 10.1038/srep12116

Glycopeptide analogues of PSGL-1 inhibit P-selectin in vitro and in vivo

Publication Name: Nature Communications
Publication Date: 2015-03-31
DOI: 10.1038/ncomms7387

Site-selective solid phase synthesis of carbonylated peptides

Publication Name: Amino Acids
Publication Date: 2015-03-27
DOI: 10.1007/s00726-015-1967-4