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Chem Impex
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Product Information

Product Name
Boc-O-tert-butyl-L-threonine
Brand Name
Chem Impex
Product Number
01385
CAS
13734-40-2
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
7015770
IUPAC Name
(2S,3R)-3-(2-methylpropan-2-yl)oxy-2-(2-methylpropan-2-yl)oxycarbonylaminobutanoic acid
InChI Key
LKRXXARJBFBMCE-BDAKNGLRSA-N
SMILES
CC@H(C@@H(C(=O)O)NC(=O)OC(C)(C)C)OC(C)(C)C

Application

Boc-O-tert-butyl-L-threonine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a protecting group for amino acids during peptide synthesis, allowing for the selective modification of specific sites without affecting others. This is crucial in creating complex peptides for pharmaceuticals.

Drug Development: It plays a significant role in the development of new therapeutic agents, particularly in the design of peptide-based drugs, enhancing their stability and bioavailability.

Bioconjugation: The compound is used in bioconjugation processes, where it helps in attaching biomolecules to other molecules, improving the efficacy of drug delivery systems.

Research in Protein Engineering: Researchers utilize it to modify proteins, allowing for the study of protein interactions and functions, which is vital in understanding diseases and developing treatments.

Analytical Chemistry: It is employed as a standard in analytical methods, helping in the quantification and characterization of amino acids and peptides in various samples.

References Data Source From Pubchem

C(sp2)—H Alkylation of Carboxylic Acids

Publication Name: Science of Synthesis
Publication Date: 2024

Chemoproteomic Profiling of Adenylation Domain Functions in Gramicidin S-Producing Non-ribosomal Peptide Synthetases

Publication Name: Non-Ribosomal Peptide Biosynthesis and Engineering
Publication Date: 2023
DOI: 10.1007/978-1-0716-3214-7_4

Serine/Threonine Ligation and Cysteine/Penicillamine Ligation

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2022-06-28
DOI: 10.1007/978-1-0716-2489-0_3

Organocatalyzed Oxa-Diels–Alder Reactions: Recent Progress

Publication Name: Synthesis
Publication Date: 2021-07-13
DOI: 10.1055/a-1514-1049

Screening of efficient siRNA carriers in a library of surface-engineered dendrimers

Publication Name: Scientific Reports
Publication Date: 2016-04-28
DOI: 10.1038/srep25069