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Sku CI28474_5_G
Chem Impex
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Product Information

Product Name
2-Amino-4-(4-fluorophenyl)-1,3-thiazole
Brand Name
Chem Impex
Product Number
28474
CAS
77815-14-6
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
722371
IUPAC Name
4-(4-fluorophenyl)-1,3-thiazol-2-amine
InChI Key
WSOKJBHBMAGBIP-UHFFFAOYSA-N
SMILES
C1=CC(=CC=C1C2=CSC(=N2)N)F

Application

2-Amino-4-(4-fluorophenyl)-1,3-thiazole is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a crucial intermediate in the synthesis of various pharmaceuticals, particularly those targeting cancer and infectious diseases, due to its ability to inhibit specific biological pathways.

Agricultural Chemicals: It is employed in the formulation of agrochemicals, enhancing crop protection products by acting as a fungicide or herbicide, which helps in improving yield and reducing crop losses.

Material Science: The compound is used in the development of novel materials, such as polymers and coatings, which exhibit improved thermal and mechanical properties, making them suitable for various industrial applications.

Biochemical Research: Researchers utilize it to study enzyme interactions and metabolic pathways, providing insights into disease mechanisms and potential therapeutic targets.

Diagnostics: It is also explored in the development of diagnostic agents, particularly in imaging techniques, where its unique properties can enhance the contrast and accuracy of medical imaging.

References Data Source From Pubchem

Discovery of small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase

Publication Name: Journal of Enzyme Inhibition and Medicinal Chemistry
Publication Date: 2022-05-05
DOI: 10.1080/14756366.2022.2070909

Synthetically-tailored and nature-derived dual COX-2/5-LOX inhibitors: Structural aspects and SAR

Publication Name: European Journal of Medicinal Chemistry
Publication Date: 2021-12-05
DOI: 10.1016/j.ejmech.2021.113804

Identification and Metabolite Profiling of Chemical Activators of Lipid Accumulation in Green Algae

Publication Name: Plant Physiology
Publication Date: 2017-06-26
DOI: 10.1104/pp.17.00433

Promiscuous 2-Aminothiazoles (PrATs): A Frequent Hitting Scaffold

Publication Name: Journal of Medicinal Chemistry
Publication Date: 2015-01-16
DOI: 10.1021/jm501402x

A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum

Publication Name: Journal of biomolecular screening
Publication Date: 2014-07
DOI: 10.1177/1087057114528738