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Sku CI35202_250_MG
Chem Impex
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Product Information

Product Name
Fmoc-allyl-L-serine
Brand Name
Chem Impex
Product Number
35202
CAS
704910-17-8
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
58427253
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-prop-2-enoxypropanoic acid
InChI Key
BFEBKKIRUYSHKY-IBGZPJMESA-N
SMILES
C=CCOCC@@H(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

Application

Fmoc-allyl-L-serine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS). Its Fmoc protecting group allows for easy deprotection, facilitating the assembly of complex peptide sequences.

Drug Development: In pharmaceutical research, Fmoc-allyl-L-serine can be used to create peptide-based drugs. Its unique structure can enhance the bioactivity of therapeutic peptides, making it valuable in drug formulation.

Bioconjugation: The allyl group in this compound allows for selective bioconjugation reactions, enabling researchers to attach various biomolecules to peptides. This application is essential in developing targeted therapies and diagnostics.

Protein Engineering: This chemical is useful in modifying proteins to improve their stability and function. By incorporating Fmoc-allyl-L-serine into proteins, researchers can enhance their properties for various applications, including enzyme catalysis and antibody development.

Research in Chemical Biology: It plays a significant role in studying protein interactions and functions. By utilizing this compound, researchers can explore the effects of specific amino acid modifications on protein behavior, aiding in the understanding of biological processes.

References Data Source From Pubchem

Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7

Publication Name: Scientific Reports
Publication Date: 2016-06-03
DOI: 10.1038/srep27060