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Sku CI06284_1_G
Chem Impex
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Product Information

Product Name
L-Cycloserine
Brand Name
Chem Impex
Product Number
06284
CAS
339-72-0
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
449215
IUPAC Name
(4S)-4-amino-1,2-oxazolidin-3-one
InChI Key
DYDCUQKUCUHJBH-REOHCLBHSA-N
SMILES
C1C@@H(C(=O)NO1)N

Application

L-Cycloserine is widely utilized in research focused on

Antibiotic Development: L-Cycloserine is primarily used in the development of antibiotics, particularly against tuberculosis. Its ability to inhibit bacterial cell wall synthesis makes it a crucial compound in the fight against resistant strains.

Neuroscience Research: This compound is explored for its potential in treating neurological disorders, including anxiety and depression, due to its role as a glycine site agonist on NMDA receptors, which are involved in synaptic plasticity.

Pharmaceutical Formulations: In the pharmaceutical industry, L-Cycloserine is incorporated into various formulations aimed at treating infections, providing a valuable option for patients with limited treatment alternatives.

Research on Antimicrobial Resistance: Researchers utilize L-Cycloserine to study mechanisms of resistance in bacteria, helping to develop strategies to combat antibiotic resistance, a significant global health challenge.

Biochemical Studies: The compound is used in biochemical assays to understand enzyme activity and metabolic pathways, aiding researchers in drug discovery and development processes.

References Data Source From Pubchem

Chemical Probes to Investigate Central Nervous System Disorders: Design, Synthesis and Mechanism of Action of a Potent Human Serine Racemase Inhibitor

Publication Name: ACS Medicinal Chemistry Letters
Publication Date: 2024-07-03
DOI: 10.1021/acsmedchemlett.4c00174

Modulators for palmitoylation of proteins and small molecules

Publication Name: European Journal of Medicinal Chemistry
Publication Date: 2024-05-05
DOI: 10.1016/j.ejmech.2024.116408

Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel

Publication Name: iScience
Publication Date: 2024-02-16
DOI: 10.1016/j.isci.2024.108907

Multimodal action of KRP203 on phosphoinositide kinases in vitro and in cells

Publication Name: Biochemical and Biophysical Research Communications
Publication Date: 2023-10-30
DOI: 10.1016/j.bbrc.2023.08.050