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Chem Impex
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Product Information

Product Name
Fmoc-O-benzyl-L-serine
Brand Name
Chem Impex
Product Number
02453
CAS
83792-48-7
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
7017914
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylmethoxypropanoic acid
InChI Key
DYBDGLCDMLNEMJ-QHCPKHFHSA-N
SMILES
C1=CC=C(C=C1)COCC@@H(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

Application

Fmoc-O-benzyl-L-serine is widely utilized in research focused on

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS). Its protective groups facilitate the sequential addition of amino acids, leading to high-purity peptide products.

Drug Development: In pharmaceutical research, it is used to create peptide-based drugs. Its unique structure allows for the development of compounds with enhanced stability and bioactivity, making it valuable in therapeutic applications.

Bioconjugation: Fmoc-O-benzyl-L-serine can be employed in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules. This is particularly useful in creating targeted drug delivery systems and diagnostic tools.

Protein Engineering: Researchers utilize this compound to modify proteins, enhancing their properties such as solubility and stability. This is crucial in developing proteins for industrial applications, including enzymes and antibodies.

Research in Neuroscience: Its application in synthesizing neuropeptides allows for the exploration of neurological pathways and the development of potential treatments for neurological disorders.

References Data Source From Pubchem

Heterogeneous Catalysis

Publication Name: Science of Synthesis
Publication Date: 2017

Design, synthesis and catalytic activity of a serine protease synthetic model

Publication Name: International Journal of Peptide Research and Therapeutics
Publication Date: 1997-12
DOI: 10.1007/bf02442921|10.1023/a:1008870113215