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Sku CI02452_100_G
Chem Impex
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Product Information

Product Name
Fmoc-L-serine
Brand Name
Chem Impex
Product Number
02452
CAS
73724-45-5
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
6541433
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxypropanoic acid
InChI Key
JZTKZVJMSCONAK-INIZCTEOSA-N
SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC@@H(CO)C(=O)O

Application

Fmoc-L-serine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the selective modification of amino acids while preventing unwanted reactions.

Bioconjugation: It is used in the development of bioconjugates, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial in drug delivery systems.

Protein Engineering: Researchers employ Fmoc-L-serine in the design of novel proteins with enhanced properties, aiding in the creation of therapeutic proteins and enzymes.

Analytical Chemistry: This chemical is utilized in various analytical techniques, such as chromatography, to separate and analyze complex mixtures of amino acids and peptides.

Pharmaceutical Development: It plays a role in the synthesis of pharmaceutical compounds, particularly those targeting neurological disorders, due to its structural similarity to neurotransmitters.

References Data Source From Pubchem

Water-based coupling of amino acids for sustainable solid-phase peptide synthesis

Publication Name: Nature Sustainability
Publication Date: 2026-02-03
DOI: 10.1038/s41893-025-01761-z

Allosteric activation of RNF20/RNF40–RAD6A-mediated H2BK120 monoubiquitylation by H2BS112 GlcNAcylation

Publication Name: Nature Chemical Biology
Publication Date: 2026-01-06
DOI: 10.1038/s41589-025-02109-6

Generation of Oxyphosphonium Ions by Photoredox/Cobaloxime Catalysis for Scalable Amide and Peptide Synthesis in Batch and Continuous Flow

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2025
DOI: 10.1007/978-1-0716-4562-8_5

Cyclic Peptide Conjugate Vaccines and Physically Mixed Cyclic Peptide Vaccines for Subcutaneous Immunization

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2024
DOI: 10.1007/978-1-0716-3914-6_9

Synthesis of alamandine glycoside analogs as new drug candidates to antagonize the MrgD receptor for pain relief

Publication Name: Medicinal Chemistry Research
Publication Date: 2022-04-08
DOI: 10.1007/s00044-022-02881-3