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Chem Impex
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Product Information

Product Name
4-Hydroxy-2-(trifluoromethyl)quinoline
Brand Name
Chem Impex
Product Number
28099
CAS
1701-18-4
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
314576
IUPAC Name
2-(trifluoromethyl)-1H-quinolin-4-one
InChI Key
SUNAMHNJYSQUPL-UHFFFAOYSA-N
SMILES
C1=CC=C2C(=C1)C(=O)C=C(N2)C(F)(F)F

Application

4-Hydroxy-2-(trifluoromethyl)quinoline is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a valuable intermediate in the synthesis of various pharmaceuticals, particularly in the development of anti-inflammatory and antimicrobial agents.

Fluorescent Probes: Its unique structure allows it to be used in creating fluorescent probes for biological imaging, aiding researchers in visualizing cellular processes.

Analytical Chemistry: Employed in chromatography as a derivatizing agent, it enhances the detection of certain analytes, improving the accuracy of chemical analyses.

Material Science: The compound is used to develop advanced materials with specific optical properties, making it relevant in the production of coatings and polymers.

Environmental Monitoring: It can be utilized in the detection of pollutants in water and soil, providing essential data for environmental protection efforts.

References Data Source From Pubchem

Multimodal action of KRP203 on phosphoinositide kinases in vitro and in cells

Publication Name: Biochemical and Biophysical Research Communications
Publication Date: 2023-10-30
DOI: 10.1016/j.bbrc.2023.08.050

Identification of 5-(Aryl/Heteroaryl)amino-4-quinolones as Potent Membrane-Disrupting Agents to Combat Antibiotic-Resistant Gram-Positive Bacteria

Publication Name: Journal of Medicinal Chemistry
Publication Date: 2022-10-11
DOI: 10.1021/acs.jmedchem.2c01151

A quantitative high-throughput screen identifies compounds that lower expression of the SCA2-and ALS-associated gene ATXN2

Publication Name: The Journal of biological chemistry
Publication Date: 2022-08
DOI: 10.1016/j.jbc.2022.102228

A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway

Publication Name: Journal of biomolecular screening
Publication Date: 2016-07
DOI: 10.1177/1087057116635503