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Sku CI17626_5_G
Chem Impex
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Product Information

Product Name
5-Amino-2,4-dichloropyrimidine
Brand Name
Chem Impex
Product Number
17626
CAS
5177-27-5
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
257797
IUPAC Name
2,4-dichloropyrimidin-5-amine
InChI Key
RINHVELYMZLXIW-UHFFFAOYSA-N
SMILES
C1=C(C(=NC(=N1)Cl)Cl)N

Application

5-Amino-2,4-dichloropyrimidine is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of antiviral and anticancer agents, enhancing drug efficacy.

Agricultural Chemicals: It is used in the formulation of herbicides and pesticides, contributing to effective weed control and crop protection, which is essential for sustainable agriculture.

Biochemical Research: Researchers employ this compound in studies related to nucleic acid metabolism and enzyme inhibition, aiding in the understanding of genetic processes and potential therapeutic targets.

Material Science: It finds applications in the development of specialty polymers and coatings, improving material properties such as durability and resistance to environmental factors.

Analytical Chemistry: This compound is utilized as a standard in various analytical techniques, ensuring accurate measurements and reliable results in laboratory settings.

References Data Source From Pubchem

General Route to Purin-2-ylmagnesium Halides by Metal–Halogen Exchange in Dichloromethane

Publication Name: Synlett
Publication Date: 2020-02-10
DOI: 10.1055/s-0039-1690818

Synthesis, reactivity, and biological activity of 5-aminouracil and its derivatives

Publication Name: Molecular Diversity
Publication Date: 2015-04-30
DOI: 10.1007/s11030-015-9595-1

Biological N-oxidation of adenine and 9-alkyl derivatives

Publication Name: European Journal of Drug Metabolism and Pharmacokinetics
Publication Date: 1987-10
DOI: 10.1007/bf03189906

Synthesis of 4-chloro-1,2,3-triazole derivatives by diazotization of 6-substituted 5-amino-4-chloropyrimidines

Publication Name: Chemistry of Heterocyclic Compounds
Publication Date: 1983-10
DOI: 10.1007/bf00505769

Sigma complexes in the pyrimidine series. 6. Reaction of 5-nitro-2-methoxy- and 5-nitro-4,6-dimethoxypyrimidines with the acetylacetone carbanion

Publication Name: Chemistry of Heterocyclic Compounds
Publication Date: 1983-10
DOI: 10.1007/bf00505768