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Product Information

Product Name
1-Phenyl-1H-pyrazole-4-carboxylic acid
Brand Name
Chem Impex
Product Number
17141
CAS
1134-50-5
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
121026
IUPAC Name
1-phenylpyrazole-4-carboxylic acid
InChI Key
ZROILLPDIUNLSE-UHFFFAOYSA-N
SMILES
C1=CC=C(C=C1)N2C=C(C=N2)C(=O)O

Application

1-Phenyl-1H-pyrazole-4-carboxylic acid is widely utilized in research focused on:

Agricultural Chemistry: This compound serves as an important building block in the synthesis of agrochemicals, particularly herbicides and fungicides, enhancing crop protection and yield.

Pharmaceutical Development: It is used in the design of novel pharmaceuticals, especially in the development of anti-inflammatory and analgesic drugs, providing potential therapeutic benefits with fewer side effects.

Material Science: The compound is explored for its role in creating advanced materials, such as polymers and coatings, which offer improved durability and resistance to environmental factors.

Biochemistry: It acts as a valuable reagent in biochemical assays, aiding researchers in studying enzyme activities and metabolic pathways, which can lead to breakthroughs in understanding diseases.

Analytical Chemistry: This chemical is employed in various analytical techniques, including chromatography and spectroscopy, for the detection and quantification of other compounds in complex mixtures.

References Data Source From Pubchem

BindingDB in 2024: a FAIR knowledgebase of protein-small molecule binding data

Publication Name: Nucleic Acids Research
Publication Date: 2024-11-22
DOI: 10.1093/nar/gkae1075

Design, synthesis, and evaluation of thiazolecarboxamide derivatives as stimulator of interferon gene inhibitors

Publication Name: Molecular Diversity
Publication Date: 2024-04-29
DOI: 10.1007/s11030-024-10860-6

Synthesis, Anti-Inflammatory Activity and Molecular Docking Studies of New 1,2,4-Triazolo[3,4-b][1,3,4]Thiadiazine Derivatives

Publication Name: Pharmaceutical Chemistry Journal
Publication Date: 2023-05
DOI: 10.1007/s11094-023-02873-6

Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking

Publication Name: Science Advances
Publication Date: 2021-04-16
DOI: 10.1126/sciadv.abf8711

Anti-inflammatory effect of a new piperazine derivative: (4-methylpiperazin-1-yl)(1-phenyl-1H-pyrazol-4-yl)methanone

Publication Name: Inflammopharmacology
Publication Date: 2017-08-20
DOI: 10.1007/s10787-017-0390-8