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Product Information

Product Name
(2S, 4S)-N-Boc-4-trifluoromethylproline
Brand Name
Chem Impex
Product Number
29119
CAS
470482-41-8
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
11426084
IUPAC Name
(2S,4S)-1-(2-methylpropan-2-yl)oxycarbonyl-4-(trifluoromethyl)pyrrolidine-2-carboxylic acid
InChI Key
OHIYKPXMNWXZQH-BQBZGAKWSA-N
SMILES
CC(C)(C)OC(=O)N1CC@H(CC@H1C(=O)O)C(F)(F)F

Application

(2S, 4S)-N-Boc-4-trifluoromethylproline is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key building block in the synthesis of novel pharmaceuticals, particularly in the development of peptide-based drugs that target specific biological pathways.

Protein Engineering: It is used in the design of modified peptides and proteins, enhancing their stability and bioactivity, which is crucial for therapeutic applications.

Research in Neuroscience: The compound is valuable in studying neurotransmitter systems, as it can be incorporated into molecules that interact with receptors, aiding in the understanding of neurological disorders.

Material Science: Its unique properties allow for the creation of advanced materials with specific chemical functionalities, which can be applied in coatings and polymers.

Agrochemical Formulations: The compound finds applications in the development of agrochemicals, where it can enhance the efficacy of crop protection agents, contributing to sustainable agriculture practices.

References Data Source From Pubchem

Synthesis of Halogenated Carboxylic Acids and Amino Acids

Publication Name: Synthesis
Publication Date: 2010-01-25
DOI: 10.1055/s-0029-1218649|10.1055/s-0029-1218805

Stereoselective Synthesis of Boc-Protectedcisandtrans-4-Trifluoromethylprolines by Asymmetric Hydrogenation Reactions

Publication Name: Angewandte Chemie (International ed. in English)
Publication Date: 2002-05-02
DOI: 10.1002/1521-3773(20020503)41:9<1600::aid-anie1600>3.0.co;2-v

CCDC 188090: Experimental Crystal Structure Determination

Publication Date: 2002
DOI: 10.5517/cc69qfm