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Sku CI16866_100_MG
Chem Impex
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Product Information

Product Name
Fmoc-D-b-homoproline
Brand Name
Chem Impex
Product Number
16866
CAS
193693-61-7
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
6957999
IUPAC Name
2-(2R)-1-(9H-fluoren-9-ylmethoxycarbonyl)pyrrolidin-2-ylacetic acid
InChI Key
ZNIGOUDZWCDFFC-CQSZACIVSA-N
SMILES
C1CC@@H(N(C1)C(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)CC(=O)O

Application

Fmoc-D-b-homoproline is widely utilized in research focused on:

Peptide Synthesis: This compound serves as an important building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity.

Drug Development: Researchers leverage Fmoc-D-b-homoproline in the design of peptide-based drugs, especially in the development of therapeutics targeting specific biological pathways, enhancing efficacy and reducing side effects.

Protein Engineering: It is used to modify proteins and enzymes, enabling scientists to study structure-function relationships and improve the stability and activity of proteins in various applications.

Bioconjugation: This chemical facilitates the attachment of biomolecules to surfaces or other molecules, which is crucial in creating targeted drug delivery systems and diagnostic tools.

Research in Neuroscience: Fmoc-D-b-homoproline is explored in studies related to neuropeptides, contributing to the understanding of neural signaling and potential treatments for neurological disorders.

References Data Source From Pubchem

De novo development of small cyclic peptides that are orally bioavailable

Publication Name: Nature Chemical Biology
Publication Date: 2023-12-28
DOI: 10.1038/s41589-023-01496-y