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Product Information

Product Name
Boc-4-oxo-L-proline
Brand Name
Chem Impex
Product Number
16571
CAS
84348-37-8
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
11593804
IUPAC Name
(2S)-1-(2-methylpropan-2-yl)oxycarbonyl-4-oxopyrrolidine-2-carboxylic acid
InChI Key
CKYGSXRXTIKGAJ-ZETCQYMHSA-N
SMILES
CC(C)(C)OC(=O)N1CC(=O)CC@H1C(=O)O

Application

Boc-4-oxo-L-proline is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of biologically active compounds. Its protective Boc (tert-butyloxycarbonyl) group allows for selective reactions, enhancing the efficiency of peptide assembly.

Drug Development: In pharmaceutical research, Boc-4-oxo-L-proline is explored for its potential in creating novel drug candidates. Its unique structure can lead to compounds with improved efficacy and specificity, addressing unmet medical needs.

Biochemical Studies: Researchers utilize this compound to study enzyme interactions and metabolic pathways. Its role in various biochemical processes helps in understanding disease mechanisms and developing targeted therapies.

Material Science: The compound is investigated for its application in creating advanced materials, such as polymers and hydrogels, which can be used in drug delivery systems or tissue engineering, providing innovative solutions in medical technology.

Analytical Chemistry: Boc-4-oxo-L-proline is employed as a standard in analytical methods, aiding in the quantification of related compounds in complex mixtures, thus enhancing the accuracy of analytical results in various research fields.

References Data Source From Pubchem

Synthesis of (+)-Oxo-tomaymycin

Publication Name: Synfacts
Publication Date: 2020-07-21
DOI: 10.1055/s-0040-1707092

Synthesis of 4-(Arylmethyl)proline Derivatives

Publication Name: Synlett
Publication Date: 2019-01-25
DOI: 10.1055/s-0037-1611672

Synthesis of an HCV Protease Inhibitor

Publication Name: Synfacts
Publication Date: 2015-03-18
DOI: 10.1055/s-0034-1380333

Practical Synthesis of Boc-Protected cis-4-Trifluoromethyl and cis-4-Difluoromethyl-l- prolines

Publication Name: The Journal of Organic Chemistry
Publication Date: 2002-09-11
DOI: 10.1021/jo0257400