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Sku CI16536_1_G
Chem Impex
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Product Information

Product Name
Boc-cis-4-fluoro-L-proline
Brand Name
Chem Impex
Product Number
16536
CAS
203866-13-1
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
2756017
IUPAC Name
(2S,4S)-4-fluoro-1-(2-methylpropan-2-yl)oxycarbonylpyrrolidine-2-carboxylic acid
InChI Key
YGWZXQOYEBWUTH-BQBZGAKWSA-N
SMILES
CC(C)(C)OC(=O)N1CC@H(CC@H1C(=O)O)F

Application

Boc-cis-4-fluoro-L-proline is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of peptide-based drugs, enhancing their stability and bioactivity.

Drug Development: Its unique fluorinated structure can improve the pharmacological properties of drug candidates, making it a key component in medicinal chemistry for creating more effective therapeutics.

Biotechnology: In the field of biotechnology, it is used to modify proteins, allowing researchers to explore new functionalities and improve the performance of biopharmaceuticals.

Research on Protein Folding: This compound aids in studying protein folding and stability, providing insights that can lead to advancements in understanding diseases related to protein misfolding.

Material Science: Boc-cis-4-fluoro-L-proline is also explored in the development of novel materials, particularly in creating polymers with enhanced properties for various industrial applications.

References Data Source From Pubchem

Polar and Helical Isomorphous Crystals of Proline Derivatives: Influence of a Fluorine Atom on the Electric Susceptibility

Publication Name: Chemistry Africa
Publication Date: 2021-03-15
DOI: 10.1007/s42250-021-00236-w

Tactical Applications of Fluorine in Drug Design and Development

Publication Name: Fluorine in Heterocyclic Chemistry Volume 1
Publication Date: 2014
DOI: 10.1007/978-3-319-04346-3_1

Propanephosphonic Acid Anhydride (T3P®) - A Benign Reagent for Diverse Applications Inclusive of Large-Scale Synthesis

Publication Name: Synthesis
Publication Date: 2013-06-03
DOI: 10.1055/s-0033-1338989