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Sku CI15937_250_MG
Chem Impex
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Product Information

Product Name
(R)-g-(4-Trifluoromethylbenzyl)-L-proline·HCl
Brand Name
Chem Impex
Product Number
15937
CAS
1049743-68-1
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
2762030
IUPAC Name
(2S,4R)-4-4-(trifluoromethyl)phenylmethylpyrrolidine-2-carboxylic acid;hydrochloride
InChI Key
LZNHALZTDTVONZ-XQKZEKTMSA-N
SMILES
C1C@H(CNC@@H1C(=O)O)CC2=CC=C(C=C2)C(F)(F)F.Cl

Application

(R)-g-(4-Trifluoromethylbenzyl)-L-proline·HCl is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key building block in the synthesis of novel pharmaceuticals, particularly in the development of drugs targeting neurological disorders due to its structural properties that enhance bioactivity.

Peptide Synthesis: It is employed in the synthesis of peptides, where its unique trifluoromethyl group can improve the stability and solubility of the resulting compounds, making it valuable in drug formulation.

Biochemical Research: Researchers use it to study protein interactions and enzyme activities, as it can act as a potent inhibitor or modulator, providing insights into biological pathways and mechanisms.

Material Science: The compound finds applications in the development of advanced materials, particularly in creating polymers with enhanced thermal and chemical resistance, which are crucial in various industrial applications.

Analytical Chemistry: It is utilized as a standard in analytical methods, helping to calibrate instruments and validate techniques in laboratories, thereby ensuring accurate and reliable results in chemical analysis.

References Data Source From Pubchem

Structure activity relationships of benzylproline-derived inhibitors of the glutamine transporter ASCT2

Publication Name: Bioorganic & Medicinal Chemistry Letters
Publication Date: 2017-02-01
DOI: 10.1016/j.bmcl.2016.12.063