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Sku CI11436_250_MG
Chem Impex
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Product Information

Product Name
cis-4-Fluoro-L-proline
Brand Name
Chem Impex
Product Number
11436
CAS
2438-57-5
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
10057550
IUPAC Name
(2S,4S)-4-fluoropyrrolidine-2-carboxylic acid
InChI Key
ZIWHMENIDGOELV-IMJSIDKUSA-N
SMILES
C1C@@H(CNC@@H1C(=O)O)F

Description

cis-4-Fluoro-L-proline is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a building block in the synthesis of novel drugs, particularly in the development of antiviral and anticancer agents, enhancing therapeutic efficacy.

Peptide Synthesis: It is incorporated into peptides to modify their properties, improving stability and bioactivity, which is crucial in drug design and protein engineering.

Neuroscience Research: Researchers use it to study neurotransmitter systems, as it can influence the activity of certain receptors, providing insights into neurological disorders.

Biochemical Studies: Its unique fluorine atom allows for better tracking in metabolic studies, making it valuable in understanding metabolic pathways and enzyme functions.

Material Science: The compound is explored for its potential in creating new materials with specific properties, such as enhanced mechanical strength or thermal stability.

References Data Source From Pubchem

Recent Trends in Diagnostic Biomarkers of Tumor Microenvironment

Publication Name: Molecular Imaging and Biology
Publication Date: 2022-12-14
DOI: 10.1007/s11307-022-01795-1

Pyrrolidine in Drug Discovery: A Versatile Scaffold for Novel Biologically Active Compounds

Publication Name: Topics in current chemistry (Cham)
Publication Date: 2021-08-10
DOI: 10.1007/s41061-021-00347-5

Evaluating the role of puckering and fluorine atom in stability and folding of fluoroproline containing proteins

Publication Name: Biotechnology and Bioprocess Engineering
Publication Date: 2017-09
DOI: 10.1007/s12257-017-0257-2

Protein Building Blocks and the Expansion of the Genetic Code

Publication Name: Synthetic Biology
Publication Date: 2016
DOI: 10.1007/978-3-319-22708-5_4

Engineering thermal properties of elastin-like polypeptides by incorporation of unnatural amino acids in a cell-free protein synthesis system

Publication Name: Biotechnology and Bioprocess Engineering
Publication Date: 2015-06
DOI: 10.1007/s12257-015-0190-1