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Sku CI07844_1_G
Chem Impex
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Product Information

Product Name
Boc-L-trans-4-hydroxyproline tert-butyl ester
Brand Name
Chem Impex
Product Number
07844
CAS
170850-75-6
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
7408710
IUPAC Name
ditert-butyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
InChI Key
OXHIVNUWGSCHBD-ZJUUUORDSA-N
SMILES
CC(C)(C)OC(=O)C@@H1CC@H(CN1C(=O)OC(C)(C)C)O

Application

Boc-L-trans-4-hydroxyproline tert-butyl ester is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of bioactive peptides that can be used in pharmaceuticals.

Drug Development: It plays a significant role in medicinal chemistry, where it is used to modify drug candidates to enhance their stability and bioavailability.

Protein Engineering: The compound is valuable in the field of protein engineering, allowing researchers to create modified proteins with improved properties for therapeutic applications.

Biotechnology: In biotechnological applications, it is used to produce modified amino acids that can improve the efficacy of biopharmaceuticals.

Research in Structural Biology: This chemical is also employed in structural biology studies, helping scientists understand protein structures and interactions, which is crucial for drug design.

References Data Source From Pubchem

Poly (vinyl alcohol)-graft-Poly (ethylene glycol) Supported Hydroxyproline: Synthesis and Application in the Enantioselective Aldol Condensation

Publication Name: Advances in Experimental Medicine and Biology
Publication Date: 2009
DOI: 10.1007/978-0-387-73657-0_103