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Chem Impex
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Product Information

Product Name
Z-L-proline tert-butyl ester
Brand Name
Chem Impex
Product Number
06560
CAS
16881-39-3
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
7019799
IUPAC Name
1-O-benzyl 2-O-tert-butyl (2S)-pyrrolidine-1,2-dicarboxylate
InChI Key
OULMZZGGALAOLR-AWEZNQCLSA-N
SMILES
CC(C)(C)OC(=O)C@@H1CCCN1C(=O)OCC2=CC=CC=C2

Application

Z-L-proline tert-butyl ester is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of pharmaceuticals. Its unique structure allows for the formation of stable linkages, enhancing the efficiency of peptide assembly.

Drug Development: In medicinal chemistry, it is used to create proline derivatives that can improve the bioavailability and efficacy of drug candidates, making it essential for researchers working on new therapeutic agents.

Chiral Catalysis: The compound acts as a chiral auxiliary in asymmetric synthesis, helping chemists produce enantiomerically pure compounds. This is particularly beneficial in the production of chiral drugs, which often require high purity for effectiveness.

Bioconjugation: It is employed in bioconjugation processes to attach biomolecules to surfaces or other molecules, facilitating the development of targeted drug delivery systems and diagnostic tools in biotechnology.

Material Science: The compound finds applications in the development of polymers and materials, where its properties can enhance the performance and stability of the final products, making it valuable in industries such as coatings and adhesives.

References Data Source From Pubchem

Captopril

Publication Name: Pharmaceutical Substances
Publication Date: 2003

The synthesis of isomeric 4-prolinylamines and 4,4′-diprolinylamines

Publication Name: Russian Journal of Bioorganic Chemistry
Publication Date: 2000-08
DOI: 10.1007/bf02759631

Blocking of the α-Carboxyl Group

Publication Name: The Practice of Peptide Synthesis
Publication Date: 1994
DOI: 10.1007/978-3-642-85055-4_3

New methods in peptide synthesis

Publication Name: Peptides
Publication Date: 1990
DOI: 10.1007/978-94-010-9060-5_346