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Sku CI03991_100_G
Chem Impex
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Product Information

Product Name
Boc-L-trans-4-hydroxyproline methyl ester
Brand Name
Chem Impex
Product Number
03991
CAS
74844-91-0
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
2734883
IUPAC Name
1-O-tert-butyl 2-O-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
InChI Key
MZMNEDXVUJLQAF-SFYZADRCSA-N
SMILES
CC(C)(C)OC(=O)N1CC@@H(CC@H1C(=O)OC)O

Description

Boc-L-trans-4-hydroxyproline methyl ester is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly those that require specific stereochemistry for biological activity.

Drug Development: It is used in the pharmaceutical industry to develop new drugs, especially those targeting collagen-related diseases, due to its structural similarity to proline.

Biomaterials: The compound is incorporated into biomaterials for tissue engineering, enhancing the mechanical properties and biocompatibility of scaffolds.

Research on Protein Folding: It aids researchers in studying protein folding mechanisms, providing insights into how proteins achieve their functional conformations.

Cosmetic Formulations: The compound is also explored in cosmetic applications for its potential to improve skin elasticity and hydration through collagen synthesis stimulation.

References Data Source From Pubchem

4-Fluoroproline and 4,4-Difluoroproline

Publication Name: Science of Synthesis
Publication Date: 2025

4-(Trifluoromethyl)proline

Publication Name: Science of Synthesis
Publication Date: 2025

Using (Diethylamino)sulfur Trifluoride and Sulfur Tetrafluoride

Publication Name: Science of Synthesis
Publication Date: 2025

Using PhenoFluor and AlkylFluor Reagents

Publication Name: Science of Synthesis
Publication Date: 2024

Direct Dehydroxy(trifluoromethyl)sulfanylation of Alkyl Alcohols

Publication Name: Science of Synthesis
Publication Date: 2024