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Product Information

Product Name
Z-D-proline
Brand Name
Chem Impex
Product Number
02238
CAS
6404-31-5
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
111208
IUPAC Name
(2R)-1-phenylmethoxycarbonylpyrrolidine-2-carboxylic acid
InChI Key
JXGVXCZADZNAMJ-LLVKDONJSA-N
SMILES
C1CC@@H(N(C1)C(=O)OCC2=CC=CC=C2)C(=O)O

Application

Z-D-proline is widely utilized in research focused on:

Peptide Synthesis: This compound is a valuable building block in the synthesis of peptides, particularly in the creation of cyclic peptides, which are important in drug development and therapeutic applications.

Drug Design: Its unique structure allows for the development of novel pharmaceuticals, especially in the treatment of neurological disorders, by enhancing the stability and bioavailability of drug candidates.

Protein Engineering: Z-D-proline is used to introduce conformational constraints in proteins, aiding researchers in studying protein folding and stability, which is crucial for understanding diseases.

Biotechnology: In the field of biotechnology, it serves as a chiral auxiliary in asymmetric synthesis, allowing for the production of enantiomerically pure compounds, which are essential in many applications.

Research in Metabolism: It is employed in metabolic studies to understand proline metabolism and its implications in various physiological processes, providing insights into metabolic disorders.

References Data Source From Pubchem

Enantioselective Benzylic C—H Oxidation

Publication Name: Science of Synthesis
Publication Date: 2023

An efficient lipase-catalyzed enantioselective hydrolysis of (R,S)-azolides derived from N-protected proline, pipecolic acid, and nipecotic acid

Publication Name: Applied Microbiology and Biotechnology
Publication Date: 2012-03-30
DOI: 10.1007/s00253-012-4010-7

Biotechnological production of amino acids and derivatives: current status and prospects

Publication Name: Applied Microbiology and Biotechnology
Publication Date: 2005-09-30
DOI: 10.1007/s00253-005-0155-y

Synthesis of C-8 Deuterated Glycosides of 3-Deoxy-D-manno-oct-2-ulosonic Acid (Kdo) Related to Chlamydial Lipopolysaccharides

Publication Name: Timely Research Perspectives in Carbohydrate Chemistry
Publication Date: 2002
DOI: 10.1007/978-3-7091-6130-2_15

Synthesis of All-D-Isomers in the Bradykinin Series

Publication Name: Hypotensive Peptides
Publication Date: 1966
DOI: 10.1007/978-3-642-94965-4_2