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Chem Impex
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Product Information

Product Name
Z-L-trans-4-hydroxyproline
Brand Name
Chem Impex
Product Number
02190
CAS
13504-85-3
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
391517
IUPAC Name
(2S,4R)-4-hydroxy-1-phenylmethoxycarbonylpyrrolidine-2-carboxylic acid
InChI Key
WWVCWLBEARZMAH-MNOVXSKESA-N
SMILES
C1C@H(CN(C@@H1C(=O)O)C(=O)OCC2=CC=CC=C2)O

Application

Z-L-trans-4-hydroxyproline is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a valuable building block in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting collagen-related diseases.

Biotechnology: It is used in the production of collagen and gelatin, which are essential in tissue engineering and regenerative medicine, offering enhanced biocompatibility compared to other compounds.

Cosmetic Formulations: Z-L-trans-4-hydroxyproline is incorporated into skincare products for its moisturizing properties, helping to improve skin elasticity and hydration.

Food Industry: This compound can be used as a food additive to enhance the texture and stability of certain products, providing a healthier alternative to synthetic additives.

Research in Structural Biology: It plays a crucial role in studying protein structures, particularly in understanding the stability and folding of collagen, which is vital for various biological processes.

References Data Source From Pubchem

New chiral proline-based catalysts for silicon and zirconium oxides-promoted asymmetric Biginelli reaction

Publication Name: Chemistry of Heterocyclic Compounds
Publication Date: 2018-04
DOI: 10.1007/s10593-018-2285-z

Synthesis of HCV Protease Inhibitor MK-1220

Publication Name: Synfacts
Publication Date: 2014-05-16
DOI: 10.1055/s-0033-1341262

Silica-immobilized N,O-prolinate ruthenium benzylidene complexes for catalytic applications

Publication Name: Journal of Sol-Gel Science and Technology
Publication Date: 2011-10-20
DOI: 10.1007/s10971-011-2610-9

Dimeric Cationic Amphiphilic Polyproline Helices for Mitochondrial Targeting

Publication Name: Pharmaceutical Research
Publication Date: 2011-06-07
DOI: 10.1007/s11095-011-0493-7

A Novel and Facile One-Pot Method for the Synthesis of N-Substituted Sulfamates

Publication Name: Synthesis
Publication Date: 2008-07
DOI: 10.1055/s-2008-1067156