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Chem Impex
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Product Information

Product Name
Boc-D-proline
Brand Name
Chem Impex
Product Number
01376
CAS
37784-17-1
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
688022
IUPAC Name
(2R)-1-(2-methylpropan-2-yl)oxycarbonylpyrrolidine-2-carboxylic acid
InChI Key
ZQEBQGAAWMOMAI-SSDOTTSWSA-N
SMILES
CC(C)(C)OC(=O)N1CCCC@@H1C(=O)O

Application

Boc-D-proline is widely utilized in research focused on:

Peptide Synthesis: It serves as a key building block in the synthesis of peptides, particularly in the development of pharmaceuticals and biologically active compounds.

Drug Development: Researchers leverage Boc-D-proline for its ability to enhance the stability and bioavailability of drug candidates, making it a valuable component in medicinal chemistry.

Protein Engineering: This compound is used to modify proteins, allowing scientists to study protein folding and interactions, which is crucial for understanding diseases.

Chiral Resolution: Boc-D-proline is effective in separating enantiomers in chiral synthesis, aiding in the production of optically pure compounds for various applications.

Material Science: Its unique properties are exploited in creating novel materials, such as hydrogels, which have applications in drug delivery and tissue engineering.

References Data Source From Pubchem

Asymmetric synthesis of enantioenriched lactams from cyclic ketones via Beckmann rearrangement

Publication Name: Nature Chemistry
Publication Date: 2026-02-13
DOI: 10.1038/s41557-026-02068-y

Enantioselective Benzylic C—H Oxidation

Publication Name: Science of Synthesis
Publication Date: 2023

Applications of the Horner–Wadsworth–Emmons Olefination in Modern Natural Product Synthesis

Publication Name: Synthesis
Publication Date: 2021-06-24
DOI: 10.1055/a-1493-6331

Synthesis of novel phase transfer catalysts derived from proline-mandelic acid/tartaric acid: their evaluation in enantioselective epoxidation and Darzen condensation

Publication Name: Journal of Chemical Sciences
Publication Date: 2019-02-23
DOI: 10.1007/s12039-019-1597-6|10.1007/s12039-019-1642-5