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Sku CI00036_5_G
Chem Impex
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Product Information

Product Name
Boc-O-benzyl-L-trans-4-hydroxyproline
Brand Name
Chem Impex
Product Number
00036
CAS
54631-81-1
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
11860409
IUPAC Name
(2S,4R)-1-(2-methylpropan-2-yl)oxycarbonyl-4-phenylmethoxypyrrolidine-2-carboxylic acid
InChI Key
DGIGGVANZFKXLS-KGLIPLIRSA-N
SMILES
CC(C)(C)OC(=O)N1CC@@H(CC@H1C(=O)O)OCC2=CC=CC=C2

Application

Boc-O-benzyl-L-trans-4-hydroxyproline is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly those requiring specific stereochemistry. Its unique structure allows for the introduction of hydroxyl groups, enhancing the stability and functionality of the resultant peptides.

Drug Development: In pharmaceutical research, it is used to create novel drug candidates, especially in the development of treatments for conditions like cancer and neurological disorders. Its ability to mimic natural amino acids makes it an attractive option for designing biologically active compounds.

Material Science: The compound is applied in the development of advanced materials, including hydrogels and polymers. Its properties can improve the mechanical strength and biocompatibility of these materials, making them suitable for biomedical applications.

Biotechnology: Researchers utilize it in the modification of proteins and enzymes, enhancing their activity or stability. This is particularly beneficial in industrial biotechnology, where optimized enzymes can lead to more efficient processes.

Analytical Chemistry: It is employed as a standard in various analytical methods, aiding in the quantification and characterization of complex mixtures. This application is crucial for ensuring the accuracy and reliability of experimental results.

References Data Source From Pubchem

4-Substituted Prolyl Sulfonamides as Enantioselective Organocatalysts for Aldol Reactions

Publication Name: Synthesis
Publication Date: 2005
DOI: 10.1055/s-2005-870026

Chemical-enzymatic synthesis of emerimicin IV and III, membrane-active pentadecapeptide antibiotics

Publication Name: Peptides
Publication Date: 1990
DOI: 10.1007/978-94-010-9060-5_165