Cat. No JK1010994_5_G
J&K Chemical

Product Information

Product Name
N-Boc-cis-4-Fluoro-L-proline methyl ester, 97%
Brand Name
J&K
Product Number
1010994
CAS
203866-16-4
Molecular Formula
C11H18FNO4
Molecular Weight
247.27
Certificate of Analysis (COA)​
COA not found

General Information

Synonyms
  • (2S,4S)-1-tert-Butyl-2-methyl-4-fluoropyrrolidine-1,2-dicarboxylate
  • Methyl-(2S,4S)-N-Boc-4-fluoropyrrolidine-2-carboxylate
PubChem CID
10977773
IUPAC Name
1-O-tert-butyl 2-O-methyl (2S,4S)-4-fluoropyrrolidine-1,2-dicarboxylate
InChI Key
METPQQHVRNLTRX-YUMQZZPRSA-N
SMILES
CC(C)(C)OC(=O)N1CC@H(CC@H1C(=O)OC)F

Properties

Density
1.153
Flash Point
> 110
n20D
1.448
Optical Activity
-74 to -60 ° (C=0.5 in MeOH))

Safety Information

Hazard Statement
H401
Precautionary Statement
P273
P501

References Data Source From Pubchem

4-Fluoroproline and 4,4-Difluoroproline

Publication Name: Science of Synthesis
Publication Date: 2025

Using (Diethylamino)sulfur Trifluoride and Sulfur Tetrafluoride

Publication Name: Science of Synthesis
Publication Date: 2025

Using PhenoFluor and AlkylFluor Reagents

Publication Name: Science of Synthesis
Publication Date: 2024

Using SulfoxFluor and SIF Reagents

Publication Name: Science of Synthesis
Publication Date: 2024

Recent Developments in the Deoxyfluorination of Alcohols and Phenols: New Reagents, Mechanistic Insights, and Applications

Publication Name: Synthesis
Publication Date: 2017-08-28
DOI: 10.1055/s-0036-1590881

N-Boc-cis-4-Fluoro-L-proline methyl ester, 97%

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