Product Name
Di-t-butylmethylphosphonium tetrafluoroborate, 99%
Certificate of Analysis (COA)
IUPAC Name
ditert-butyl(methyl)phosphanium tetrafluoroborate
InChI Key
BRDLRXCAHKUWJS-UHFFFAOYSA-O
SMILES
B-(F)(F)(F)F.CC(C)(C)PH+(C)C(C)(C)C
Technical Note:
1.Air and moisture-stable phosphonium salt used in palladium-catalyzed coupling reactions. The phosphoniumsaltis s deprotonated in situ to yield the free phosphine ligand. Use of the phosphonium salt furnished nearly identical product as reactions carried out using the phosphine.
2. Ligand for the Pd-catalyzed heteroaromatic direct arylation.
References:
1.J. Am. Chem. Soc., 2003, 125, 5616. 2.J. Am. hem. Soc., 2003, 125, 371 8.
3.Angew. Chem. Int. Ed., 2002, 41, 3910.
4.J. Am. Chem. Soc., 2002, 124, 13662.
5.Angew. Chem. Int. Ed., 2011, 50, 8660.
6.J. Org. Chem., 2010, 75, 1047.
Arylation
Publication Name: Science of Synthesis
Publication Date: 2024
![(R)-[1,1'-Binaphthalene]-2,2'-diylbis[1,1-diphenyl-1,1'-phosphine oxide], 98% (99% ee)|15-0312|94041-16-4](http://www.jk-sci.com/cdn/shop/files/3117e307f3d0924dbdc43a92206364d2_200x200_crop_center.jpg?v=1784770208)
