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Sku CI16836_250_MG
Chem Impex
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Product Information

Product Name
Boc-D-2,4,5-trifluorophenylalanine
Brand Name
Chem Impex
Product Number
16836
CAS
486460-09-7
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
7146200
IUPAC Name
(2R)-2-(2-methylpropan-2-yl)oxycarbonylamino-3-(2,4,5-trifluorophenyl)propanoic acid
InChI Key
FTWHJNNFVISGNQ-LLVKDONJSA-N
SMILES
CC(C)(C)OC(=O)NC@H(CC1=CC(=C(C=C1F)F)F)C(=O)O

Application

Boc-D-2,4,5-trifluorophenylalanine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of novel therapeutic agents. Its unique trifluorophenyl group enhances the stability and bioactivity of the resulting peptides.

Drug Development: Researchers leverage its properties to design and optimize drug candidates, especially in the fields of oncology and neurology, where specific targeting of receptors is crucial.

Bioconjugation: The compound is used in bioconjugation processes, allowing for the attachment of drugs to antibodies or other biomolecules, enhancing the efficacy of targeted therapies.

Fluorinated Amino Acids: Its incorporation into proteins can improve their pharmacokinetic properties, making it valuable in the study of protein structure and function, particularly in drug design.

Research in Chemical Biology: The compound is instrumental in chemical biology studies, helping scientists understand the interactions between proteins and small molecules, which is vital for the development of new therapeutic strategies.

References Data Source From Pubchem

Sitagliptin phosphate

Publication Name: Pharmaceutical Substances
Publication Date: 2007