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Product Information

Product Name
Pentafluoro-D-phenylalanine
Brand Name
Chem Impex
Product Number
15440
CAS
40332-58-9
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
6992999
IUPAC Name
(2R)-2-amino-3-(2,3,4,5,6-pentafluorophenyl)propanoic acid
InChI Key
YYTDJPUFAVPHQA-GSVOUGTGSA-N
SMILES
C(C1=C(C(=C(C(=C1F)F)F)F)F)C@H(C(=O)O)N

Application

Pentafluoro-D-phenylalanine is widely utilized in research focused on:

Drug Development: This compound serves as a building block in the synthesis of novel pharmaceuticals, particularly in designing drugs that require specific fluorinated amino acids for enhanced bioactivity.

Protein Engineering: It is used to modify proteins, allowing researchers to study the effects of fluorination on protein structure and function, which can lead to the development of more effective therapeutic proteins.

Fluorine Chemistry: The unique properties of pentafluoro-D-phenylalanine make it a valuable tool in fluorine chemistry, aiding in the exploration of new fluorinated compounds with potential applications in various chemical processes.

Biomolecular Research: This compound is instrumental in studying biomolecular interactions, helping scientists understand how fluorinated amino acids influence protein interactions and stability.

Analytical Chemistry: It is utilized in analytical methods to improve the sensitivity and selectivity of detection techniques, particularly in mass spectrometry, enhancing the analysis of complex biological samples.

References Data Source From Pubchem

Engineered Polypeptides for Tissue Engineering

Publication Name: Biomaterials for Tissue Engineering Applications
Publication Date: 2011
DOI: 10.1007/978-3-7091-0385-2_9

Synthesis and receptor binding of oxytocin analogs containing conformationally restricted amino acids

Publication Name: International Journal of Peptide Research and Therapeutics
Publication Date: 2001-01
DOI: 10.1007/bf02443576|10.1023/a:1014242727915

Analogs of oxytocin with L- and D-pentafluorophenylalanines in the second position

Publication Name: Chemistry of Natural Compounds
Publication Date: 1977-05
DOI: 10.1007/bf00573555