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Sku CI15305_100_MG
Chem Impex
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Product Information

Product Name
Fmoc-pentafluoro-D-b-homophenylalanine
Brand Name
Chem Impex
Product Number
15305
CAS
269398-94-9
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
7009773
IUPAC Name
(3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(2,3,4,5,6-pentafluorophenyl)butanoic acid
InChI Key
HCBMYXPXBOUBBR-GFCCVEGCSA-N
SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC@H(CC4=C(C(=C(C(=C4F)F)F)F)F)CC(=O)O

Application

Fmoc-pentafluoro-D-b-homophenylalanine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, where its protective Fmoc group allows for selective deprotection and coupling.

Drug Development: Its unique fluorinated structure enhances the pharmacokinetic properties of peptides, making it valuable in the design of novel therapeutics with improved efficacy and stability.

Bioconjugation: The compound can be used to create bioconjugates for targeted drug delivery systems, leveraging its ability to form stable linkages with various biomolecules.

Fluorine-Containing Compounds: Its incorporation into drug candidates can improve their metabolic stability and bioavailability, making it a preferred choice in medicinal chemistry.

Research in Protein Engineering: This chemical is instrumental in the development of modified proteins with enhanced properties, aiding researchers in studying protein interactions and functions.