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Sku CI03923_1_G
Chem Impex
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Product Information

Product Name
Fmoc-4-iodo-L-phenylalanine
Brand Name
Chem Impex
Product Number
03923
CAS
82565-68-2
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
2761479
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-iodophenyl)propanoic acid
InChI Key
LXOXXTQKKRJNNB-QFIPXVFZSA-N
SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC@@H(CC4=CC=C(C=C4)I)C(=O)O

Description

Fmoc-4-iodo-L-phenylalanine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides with specific sequences and functionalities.

Drug Development: Its unique properties make it valuable in the pharmaceutical industry for developing new drugs, particularly those targeting specific proteins or receptors.

Bioconjugation: The iodine atom in this compound facilitates bioconjugation, enabling the attachment of various biomolecules for applications in diagnostics and therapeutics.

Research in Cancer Therapeutics: The compound is being explored for its potential in cancer treatment, as it can be incorporated into peptides that selectively target cancer cells.

Fluorescent Labeling: Researchers use it for fluorescent labeling in studies involving protein interactions, enhancing the understanding of biological processes.

References Data Source From Pubchem

Applications of biaryl cyclization in the synthesis of cyclic enkephalin analogs with a highly restricted flexibility

Publication Name: Amino Acids
Publication Date: 2024-03-01
DOI: 10.1007/s00726-023-03371-5

Solid-Phase Synthesis of Biaryl Cyclic Peptides Containing a Histidine-Phenylalanine Linkage

Publication Name: International Journal of Peptide Research and Therapeutics
Publication Date: 2019-06-19
DOI: 10.1007/s10989-019-09877-5

Efficient Scaled-Up Synthesis of N-α-Fmoc-4-Phosphono(difluoromethyl)-l-phenylalanine and Its Incorporation into Peptides

Publication Name: Synthesis
Publication Date: 2011-09-06
DOI: 10.1055/s-0030-1260206

Peptide model helices in lipid membranes: insertion, positioning, and lipid response on aggregation studied by X-ray scattering

Publication Name: European biophysics journal : EBJ
Publication Date: 2010-12-23
DOI: 10.1007/s00249-010-0645-4

Synthesis of Phosphopeptides in the Fmoc Mode

Publication Name: International Journal of Peptide Research and Therapeutics
Publication Date: 2007-08-21
DOI: 10.1007/s10989-007-9107-y