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Product Information

Product Name
4-Chloro-D-phenylalanine
Brand Name
Chem Impex
Product Number
02862
CAS
14091-08-8
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
667429
IUPAC Name
(2R)-2-amino-3-(4-chlorophenyl)propanoic acid
InChI Key
NIGWMJHCCYYCSF-MRVPVSSYSA-N
SMILES
C1=CC(=CC=C1CC@H(C(=O)O)N)Cl

Application

4-Chloro-D-phenylalanine is widely utilized in research focused on:

Pharmaceutical Development: This compound is used as a building block in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting neurological disorders.

Protein Engineering: It serves as a useful tool in the study of protein structure and function, allowing researchers to incorporate chlorinated amino acids into proteins to investigate their properties.

Biochemical Research: The compound is employed in studies related to neurotransmitter activity, helping scientists understand the role of amino acids in brain function and signaling.

Anticancer Research: It has shown potential in the development of anticancer agents, providing a pathway for creating targeted therapies that can minimize side effects compared to traditional treatments.

Analytical Chemistry: This chemical is used in various analytical techniques to quantify amino acids in biological samples, enhancing the accuracy of metabolic studies.

References Data Source From Pubchem

A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome

Publication Name: Cell Reports
Publication Date: 2021-04-27
DOI: 10.1016/j.celrep.2021.109040

Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors

Publication Name: Proceedings of the National Academy of Sciences of the United States of America
Publication Date: 2020-11-23
DOI: 10.1073/pnas.2005463117

Approaches to α-Amino Acids Based on Deracemization and Stereoinversion

Publication Name: Science of Synthesis
Publication Date: 2019

Preparation Using Acylase I

Publication Name: Science of Synthesis
Publication Date: 2015

Applications in Organic Synthesis

Publication Name: Science of Synthesis
Publication Date: 2009