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Product Information

Product Name
4-Chloro-L-phenylalanine
Brand Name
Chem Impex
Product Number
02861
CAS
14173-39-8
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
736190
IUPAC Name
(2S)-2-amino-3-(4-chlorophenyl)propanoic acid
InChI Key
NIGWMJHCCYYCSF-QMMMGPOBSA-N
SMILES
C1=CC(=CC=C1CC@@H(C(=O)O)N)Cl

Application

4-Chloro-L-phenylalanine is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key building block in synthesizing various pharmaceuticals, particularly those targeting neurological disorders, due to its ability to influence neurotransmitter pathways.

Protein Engineering: Researchers use it to create modified proteins with enhanced properties, allowing for the study of protein interactions and functions, which is crucial in drug discovery and biotechnology.

Biochemical Research: It acts as an important tool in studying the effects of amino acid substitutions on enzyme activity, helping scientists understand metabolic pathways and develop targeted therapies.

Neuroscience Studies: This compound is employed in experiments to investigate the role of specific amino acids in brain function, providing insights into conditions like depression and anxiety.

Food Industry Applications: It can be used in food science research to explore the impact of amino acid profiles on flavor and nutritional value, aiding in the development of healthier food products.

References Data Source From Pubchem

Stereoselective, sex-dependent 5-HT2A receptor modulation of cortical plasticity by MDMA in mice

Publication Name: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Publication Date: 2026-02-02
DOI: 10.1038/s41386-025-02313-x

Strategies for blood–brain barrier rejuvenation and repair

Publication Name: Nature reviews. Drug discovery
Publication Date: 2026-01-28
DOI: 10.1038/s41573-025-01364-5

Self-emulsifying Drug Delivery Systems as a Paradigm for Enhancing Bioavailability of Phytoconstituents

Publication Name: Journal of Solution Chemistry
Publication Date: 2026-01-21
DOI: 10.1007/s10953-026-01564-6

Fluvoxamine attenuates inflammation in experimental sepsis via novel non-canonical pathways

Publication Name: Inflammopharmacology
Publication Date: 2025-12-15
DOI: 10.1007/s10787-025-02064-7

Integrating serum pharmacochemistry with network pharmacology and pharmacological validation to elucidate the mechanism of KaiXinSan in treating insomnia

Publication Name: BMC Complementary Medicine and Therapies
Publication Date: 2025-11-29
DOI: 10.1186/s12906-025-05196-z