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Product Information

Product Name
Boc-4-nitro-L-phenylalanine
Brand Name
Chem Impex
Product Number
02723
CAS
33305-77-0
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
7021882
IUPAC Name
(2S)-2-(2-methylpropan-2-yl)oxycarbonylamino-3-(4-nitrophenyl)propanoic acid
InChI Key
XBQADBXCNQPHHY-NSHDSACASA-N
SMILES
CC(C)(C)OC(=O)NC@@H(CC1=CC=C(C=C1)N+(=O)O-)C(=O)O

Application

Boc-4-nitro-L-phenylalanine is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing chemists to selectively modify amino acids without affecting others, which is crucial for creating complex biomolecules.

Drug Development: Its unique properties make it a valuable intermediate in the development of pharmaceuticals, particularly in designing compounds that target specific biological pathways.

Bioconjugation: The nitro group can be used in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules, which is essential in creating targeted drug delivery systems.

Research in Neuroscience: This compound can be employed in studies investigating neurotransmitter pathways, helping researchers understand the role of amino acids in brain function and disorders.

Analytical Chemistry: It is used as a standard in analytical methods to quantify amino acids in various samples, providing reliable data for researchers in food science and biochemistry.

References Data Source From Pubchem

Boc/Bzl Solid-Phase Synthesis of Deltorphin II and Its Analogs without the Utilization of Anhydrous Hydrogen Fluoride

Publication Name: Russian Journal of Bioorganic Chemistry
Publication Date: 2024-10
DOI: 10.1134/s1068162024050297

Preparation of Polymer-Based Amino Acid Stationary Phase and Its Application for Mixed-Mode Chromatography

Publication Name: Chromatographia
Publication Date: 2024-02-06
DOI: 10.1007/s10337-024-04311-5

Optical Control of CENP-E Function

Publication Name: Synfacts
Publication Date: 2020-03-18
DOI: 10.1055/s-0040-1707563

QSPR modeling of optical rotation of amino acids using specific quantum chemical descriptors

Publication Name: Journal of Molecular Modeling
Publication Date: 2018-02-17
DOI: 10.1007/s00894-018-3593-z

Synthesis and characterization of novel benzothiazole amide derivatives and screening as possible antimitotic and antimicrobial agents

Publication Name: Research on Chemical Intermediates
Publication Date: 2016-07-06
DOI: 10.1007/s11164-016-2627-3