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Product Information

Product Name
Boc-L-homophenylalanine
Brand Name
Chem Impex
Product Number
01773
CAS
100564-78-1
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
7018726
IUPAC Name
(2S)-2-(2-methylpropan-2-yl)oxycarbonylamino-4-phenylbutanoic acid
InChI Key
MCODLPJUFHPVQP-LBPRGKRZSA-N
SMILES
CC(C)(C)OC(=O)NC@@H(CCC1=CC=CC=C1)C(=O)O

Application

Boc-L-homophenylalanine is widely utilized in research focused on

Peptide Synthesis: This compound is a valuable building block in the synthesis of peptides, particularly in the development of pharmaceuticals and biologically active compounds. Its protective Boc group allows for selective reactions, enhancing the efficiency of peptide assembly.

Drug Development: Researchers leverage Boc-L-homophenylalanine in drug design to create novel therapeutic agents. Its unique structural properties can improve the bioactivity and selectivity of drug candidates, making it a preferred choice in medicinal chemistry.

Protein Engineering: In the field of biotechnology, this compound is used to modify protein structures. By incorporating it into proteins, scientists can study the effects of amino acid substitutions on protein function, stability, and interactions.

Bioconjugation: Boc-L-homophenylalanine serves as a key component in bioconjugation techniques, where it can be used to attach biomolecules to surfaces or other molecules. This application is crucial in developing targeted drug delivery systems and diagnostic tools.

Research in Neuroscience: Its structural similarity to phenylalanine allows researchers to investigate its role in neurotransmitter pathways, contributing to studies on neurological disorders and potential treatments.

References Data Source From Pubchem

Diketopiperazine-Based Peptide Mimic Scaffolds

Publication Name: Topics in Heterocyclic Chemistry
Publication Date: 2015
DOI: 10.1007/7081_2015_165

Carfilzomib

Publication Name: Pharmaceutical Substances
Publication Date: 2014

Development and Applications of Amino Acid Derived Organometallics

Publication Name: Synlett
Publication Date: 2005
DOI: 10.1055/s-2005-918950