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Product Information

Product Name
4-Nitro-L-phenylalanine
Brand Name
Chem Impex
Product Number
00431
CAS
949-99-5
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
13706
IUPAC Name
(2S)-2-amino-3-(4-nitrophenyl)propanoic acid
InChI Key
GTVVZTAFGPQSPC-QMMMGPOBSA-N
SMILES
C1=CC(=CC=C1CC@@H(C(=O)O)N)N+(=O)O-

Application

4-Nitro-L-phenylalanine is widely utilized in research focused on:

Protein Engineering: This compound serves as a useful building block for the synthesis of modified proteins, allowing researchers to study the effects of nitro groups on protein structure and function.

Drug Development: Its unique properties make it a candidate for developing novel pharmaceuticals, particularly in targeting specific enzymes or receptors in disease pathways.

Biochemical Assays: The compound is employed in various assays to measure enzyme activity and interactions, providing valuable insights into metabolic processes.

Research on Neurotransmitters: It is used in studies examining the role of amino acids in neurotransmission, helping to advance understanding of neurological disorders.

Material Science: 4-Nitro-L-phenylalanine can be incorporated into polymer matrices, enhancing material properties for applications in coatings and adhesives.

References Data Source From Pubchem

NitraTh epitope-based neoantigen vaccines for effective tumor immunotherapy

Publication Name: Cancer immunology, immunotherapy : CII
Publication Date: 2024-10-03
DOI: 10.1007/s00262-024-03830-2

Boc/Bzl Solid-Phase Synthesis of Deltorphin II and Its Analogs without the Utilization of Anhydrous Hydrogen Fluoride

Publication Name: Russian Journal of Bioorganic Chemistry
Publication Date: 2024-10
DOI: 10.1134/s1068162024050297

A Ratio Fluorescence Method Based on Dual Emissive Copper Nanoclusters for the Detection of Vanillin

Publication Name: Journal of Fluorescence
Publication Date: 2024-01-17
DOI: 10.1007/s10895-024-03582-3

A platform for distributed production of synthetic nitrated proteins in live bacteria

Publication Name: Nature Chemical Biology
Publication Date: 2023-05-15
DOI: 10.1038/s41589-023-01338-x

Self-assembled nanoparticles based on DNA origami and a nitrated T helper cell epitope as a platform for the development of personalized cancer vaccines

Publication Name: Cancer immunology, immunotherapy : CII
Publication Date: 2023-04-29
DOI: 10.1007/s00262-023-03446-y