(S)-7,7’-Bis[(4S)-(phenyl)oxazol-2-yl)]-2,2’,3,3’-tetrahydro-1,1’-spirobiindane, min. 97% (Sa,S,S)-SpiroBOX

Technical Notes:
1.Chiral ligands for copper- catalyzed asymmetric insertions of carbenoids into N- H bond of anilines.
2.Chiral ligands for copper or palladium-catalyzed asymmetric insertions of carbenoids into o -H bond of phenols.
3.Chiral ligands for copper or iron-catalyzed asymmetric insertions of carbenoids into o H bond of water.
4.Chiral ligands for copper-catalyzed asymmetric insertions of carbenoids into S-H bonds of arylmethylene mercaptans.
References:
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4.Angew. Chem., Int. Ed.. 2013, 52, 2555. 5.Angew. Chem., Int. Ed., 2014, 53, 2978
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8.Chem. Commun.. 2009, 5362.