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Sku CI25978_1_G
Chem Impex
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Product Information

Product Name
3-Phenylisoxazole-5-carboxylic acid
Brand Name
Chem Impex
Product Number
25978
CAS
14442-12-7
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
737474
IUPAC Name
3-phenyl-1,2-oxazole-5-carboxylic acid
InChI Key
YGTFDJRCCBKLDM-UHFFFAOYSA-N
SMILES
C1=CC=C(C=C1)C2=NOC(=C2)C(=O)O

Description

3-Phenylisoxazole-5-carboxylic acid is widely utilized in research focused on:

Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly those targeting neurological disorders due to its ability to modulate neurotransmitter activity.

Agricultural Chemistry: It is used in the formulation of agrochemicals, enhancing the efficacy of pesticides and herbicides by improving their stability and absorption in plants.

Material Science: The compound is explored for its potential in creating novel polymers and materials, offering improved thermal stability and mechanical properties compared to traditional compounds.

Analytical Chemistry: It acts as a standard in analytical methods, aiding researchers in the accurate quantification of related compounds in complex mixtures.

Biochemical Research: This chemical is utilized in studies investigating enzyme inhibition and receptor binding, providing insights into metabolic pathways and potential therapeutic targets.

References Data Source From Pubchem

Large-Scale Crystallographic Fragment Screening Expedites Compound Optimization and Identifies Putative Protein–Protein Interaction Sites

Publication Name: Journal of Medicinal Chemistry
Publication Date: 2022-10-19
DOI: 10.1021/acs.jmedchem.2c01165

Design and synthesis of a new series of 3,5-disubstituted isoxazoles active against Trypanosoma cruzi and Leishmania amazonensis

Publication Name: European Journal of Medicinal Chemistry
Publication Date: 2017-03-10
DOI: 10.1016/j.ejmech.2017.01.029

Design, synthesis and biological activities of novel anthranilic diamides containing dihydroisoxazoline and isoxazole

Publication Name: Chemical Research in Chinese Universities
Publication Date: 2015-11-04
DOI: 10.1007/s40242-015-5320-y

High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors

Publication Name: Antiviral Research
Publication Date: 2011-09
DOI: 10.1016/j.antiviral.2011.06.006

Activation of Carboxylic Acids

Publication Name: Science of Synthesis
Publication Date: 2011