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Chem Impex
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Product Information

Product Name
Fmoc-(3R)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
Brand Name
Chem Impex
Product Number
02602
CAS
130309-33-0
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
978342
IUPAC Name
(3R)-2-(9H-fluoren-9-ylmethoxycarbonyl)-3,4-dihydro-1H-isoquinoline-3-carboxylic acid
InChI Key
LIRBCUNCXDZOOU-HSZRJFAPSA-N
SMILES
C1C@@H(N(CC2=CC=CC=C21)C(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35)C(=O)O

Application

Fmoc-(3R)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a protecting group in solid-phase peptide synthesis, allowing for the selective modification of amino acids without interfering with other functional groups.

Drug Development: Its unique structure is beneficial in the design of novel pharmaceuticals, particularly in creating compounds that target specific biological pathways.

Bioconjugation: The chemical can be used to attach biomolecules to surfaces or other molecules, enhancing the functionality of diagnostic tools and therapeutic agents.

Research in Neuroscience: Due to its structural similarity to neurotransmitters, it is explored in studies related to neuropharmacology and the development of treatments for neurological disorders.

Organic Synthesis: This compound is a valuable intermediate in the synthesis of complex organic molecules, making it essential for researchers in organic chemistry and material science.

References Data Source From Pubchem

Synthesis of the bradykinin B1 antagonist [desArg10]HOE 140 on 2-chlorotrityl resin

Publication Name: International Journal of Peptide Research and Therapeutics
Publication Date: 1996-02
DOI: 10.1007/bf00119994