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Product Information

Product Name
Boc-(3S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
Brand Name
Chem Impex
Product Number
02599
CAS
78879-20-6
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
664088
IUPAC Name
(3S)-2-(2-methylpropan-2-yl)oxycarbonyl-3,4-dihydro-1H-isoquinoline-3-carboxylic acid
InChI Key
HFPVZPNLMJDJFB-LBPRGKRZSA-N
SMILES
CC(C)(C)OC(=O)N1CC2=CC=CC=C2CC@H1C(=O)O

Application

Boc-(3S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid is widely utilized in research focused on:

Synthesis of Pharmaceuticals: This compound serves as a key intermediate in the synthesis of various pharmaceutical agents, particularly those targeting neurological disorders. Its unique structure allows for the development of drugs with improved efficacy.

Peptide Chemistry: It is commonly used in peptide synthesis as a protecting group for amino acids, facilitating the formation of complex peptide chains while preventing unwanted reactions.

Research in Neuroscience: The compound is valuable in neuroscience research for studying neurotransmitter systems and developing potential treatments for conditions like depression and anxiety.

Organic Synthesis: Its application in organic synthesis enables chemists to create diverse chemical libraries, which are essential for drug discovery and development processes.

Biochemical Studies: The compound is utilized in biochemical assays to investigate enzyme activity and interactions, contributing to a better understanding of metabolic pathways.

References Data Source From Pubchem

Synthesis of Optically Pure (R)- and (S)-Tetrahydroisoquinoline-1- and -3-Carboxylic Acids

Publication Name: Synthesis
Publication Date: 2015-03-12
DOI: 10.1055/s-0034-1380289

Difficulties in coupling to conformationally constrained aromatic amino acids

Publication Name: International Journal of Peptide Research and Therapeutics
Publication Date: 2000-05
DOI: 10.1007/bf02443583|10.1023/a:1008928404072

Receptor selective opioid peptides: Facile solution phase assembly, suitable for scale-up

Publication Name: Peptides 1994
Publication Date: 1995
DOI: 10.1007/978-94-011-1468-4_143

X-ray structures of the δ opioid antagonist TIPP and a protected derivative of the δ opioid antagonist ICI 174,864

Publication Name: International Journal of Peptide Research and Therapeutics
Publication Date: 1994-12
DOI: 10.1007/bf00128528