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Sku CI03678_25_G
Chem Impex
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Product Information

Product Name
Boc-L-isoleucine N-hydroxysuccinimide ester
Brand Name
Chem Impex
Product Number
03678
CAS
3392-08-3
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
333451
IUPAC Name
(2,5-dioxopyrrolidin-1-yl) (2S,3S)-3-methyl-2-(2-methylpropan-2-yl)oxycarbonylaminopentanoate
InChI Key
FATJLEZSGFVHQA-CABZTGNLSA-N
SMILES
CCC@H(C)C@@H(C(=O)ON1C(=O)CCC1=O)NC(=O)OC(C)(C)C

Description

Boc-L-isoleucine N-hydroxysuccinimide ester is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, allowing researchers to create specific sequences for biological studies.

Drug Development: It is used in the development of pharmaceutical compounds, particularly in creating prodrugs that enhance bioavailability and target delivery.

Bioconjugation: The chemical is effective in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, improving the functionality of diagnostic tools.

Protein Modification: Researchers utilize it for modifying proteins to study their structure and function, which is crucial in understanding disease mechanisms.

Research in Biotechnology: This compound plays a role in various biotechnological applications, including the development of vaccines and therapeutic proteins, due to its ability to facilitate specific reactions.

References Data Source From Pubchem

Synthesis of SARS-CoV-2 Spike Glycoprotein Peptide Fragments and Study of Their Binding to Human Blood Cells

Publication Name: Russian Journal of Bioorganic Chemistry
Publication Date: 2024-10
DOI: 10.1134/s1068162024050352

Chemoproteomic Profiling of Adenylation Domain Functions in Gramicidin S-Producing Non-ribosomal Peptide Synthetases

Publication Name: Non-Ribosomal Peptide Biosynthesis and Engineering
Publication Date: 2023
DOI: 10.1007/978-1-0716-3214-7_4

Inhibition of Dipeptidylpeptidase IV (DPP IV, CD26) Activity Modulates Surface Expression of CTLA-4 in Stress-Induced Abortions

Publication Name: Dipeptidyl Aminopeptidases in Health and Disease
Publication Date: 2004
DOI: 10.1007/0-306-47920-6_19

Monitoring in Solid-Phase Peptide Synthesis

Publication Name: The Chemistry of Polypeptides
Publication Date: 1973
DOI: 10.1007/978-1-4613-4571-8_17