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Sku CI05721_5_G
Chem Impex
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Product Information

Product Name
Na-Fmoc-L-histidine
Brand Name
Chem Impex
Product Number
05721
CAS
116611-64-4
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
7019075
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1H-imidazol-5-yl)propanoic acid
InChI Key
SIRPVCUJLVXZPW-IBGZPJMESA-N
SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC@@H(CC4=CN=CN4)C(=O)O

Description

Na-Fmoc-L-histidine is widely utilized in research focused on

Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids. Its stability under various conditions makes it a preferred choice for researchers in organic chemistry.

Drug Development: In pharmaceutical research, it plays a critical role in the design of histidine-containing compounds, which are essential for developing new drugs targeting various diseases, including cancer and metabolic disorders.

Bioconjugation: Na-Fmoc-L-histidine is used in bioconjugation processes, where it helps in attaching biomolecules to surfaces or other molecules, enhancing the efficacy of drug delivery systems.

Protein Engineering: This compound is valuable in protein engineering, allowing scientists to modify proteins at specific sites, which can lead to the development of proteins with improved stability and activity.

Research on Enzyme Activity: It aids in studying enzyme mechanisms by providing a histidine residue that can participate in catalytic processes, helping researchers understand enzyme function and develop inhibitors.

References Data Source From Pubchem

Designing supramolecular catalytic systems for mammalian synthetic metabolism

Publication Name: Nature Reviews Materials
Publication Date: 2025-04-29
DOI: 10.1038/s41578-025-00801-6

Designed imidazole-based supramolecular catalysts for accelerating oxidation/hydrolysis cascade reactions

Publication Name: Nano Research
Publication Date: 2024-02-07
DOI: 10.1007/s12274-024-6489-5

Nanoarchitectonics: functional nanomaterials and nanostructures—a review

Publication Name: Journal of Nanoparticle Research
Publication Date: 2022-09-22
DOI: 10.1007/s11051-022-05577-2