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Sku CI05719_5_G
Chem Impex
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Product Information

Product Name
Na-Fmoc-Nim-Boc-L-histidine
Brand Name
Chem Impex
Product Number
05719
CAS
81379-52-4
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
11123631
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-1-(2-methylpropan-2-yl)oxycarbonylimidazol-4-ylpropanoic acid
InChI Key
ZRHPMMZWDWMKPD-QFIPXVFZSA-N
SMILES
CC(C)(C)OC(=O)N1C=C(N=C1)CC@@H(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

Description

Na-Fmoc-Nim-Boc-L-histidine is widely utilized in research focused on

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing researchers to create complex peptide sequences efficiently.

Drug Development: It is used in the development of pharmaceuticals, especially in designing histidine-containing compounds that can act as enzyme inhibitors or modulators, which are crucial in treating various diseases.

Bioconjugation: The chemical is valuable in bioconjugation techniques, where it helps in attaching biomolecules to surfaces or other molecules, enhancing the functionality of drugs and diagnostics.

Protein Engineering: It plays a significant role in protein engineering, aiding in the modification of proteins to improve their stability and activity, which is essential in biotechnology applications.

Research in Cancer Therapeutics: The compound is explored in cancer research for its potential to create targeted therapies, leveraging its ability to interact with specific biological targets in cancer cells.

References Data Source From Pubchem

Water-based coupling of amino acids for sustainable solid-phase peptide synthesis

Publication Name: Nature Sustainability
Publication Date: 2026-02-03
DOI: 10.1038/s41893-025-01761-z

Recent developments of automated flow chemistry in pharmaceutical compounds synthesis

Publication Name: Journal of Flow Chemistry
Publication Date: 2023-11-06
DOI: 10.1007/s41981-023-00285-x

New Developments in Microwave–Assisted Solid Phase Peptide Synthesis

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2020
DOI: 10.1007/978-1-0716-0227-0_6

Heterogeneous Catalysis

Publication Name: Science of Synthesis
Publication Date: 2017

Positional Scanning Substrate Combinatorial Library (PS-SCL) Approach to Define Caspase Substrate Specificity

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2014
DOI: 10.1007/978-1-4939-0357-3_2