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Sku CI03710_10_G
Chem Impex
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Product Information

Product Name
Na-Fmoc-Nim-Boc-L-histidine cyclohexylammonium salt
Brand Name
Chem Impex
Product Number
03710
CAS
81379-52-4
Certificate of Analysis (COA)​
COA not found

General Information

PubChem CID
11123631
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-1-(2-methylpropan-2-yl)oxycarbonylimidazol-4-ylpropanoic acid
InChI Key
ZRHPMMZWDWMKPD-QFIPXVFZSA-N
SMILES
CC(C)(C)OC(=O)N1C=C(N=C1)CC@@H(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

Description

Na-Fmoc-Nim-Boc-L-histidine cyclohexylammonium salt is widely utilized in research focused on:

Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex and biologically active peptides.

Drug Development: It plays a significant role in pharmaceutical research, aiding in the development of new drugs by providing a stable histidine derivative that can enhance the efficacy of therapeutic agents.

Bioconjugation: The compound is used in bioconjugation techniques, where it helps attach biomolecules to surfaces or other molecules, facilitating the development of targeted drug delivery systems.

Protein Engineering: Researchers utilize this chemical to modify proteins, enhancing their stability and activity, which is crucial for applications in biotechnology and enzyme engineering.

Diagnostics: Its properties make it valuable in diagnostic assays, where it can be used to create specific reagents that improve the sensitivity and specificity of tests for various diseases.

References Data Source From Pubchem

Water-based coupling of amino acids for sustainable solid-phase peptide synthesis

Publication Name: Nature Sustainability
Publication Date: 2026-02-03
DOI: 10.1038/s41893-025-01761-z

Recent developments of automated flow chemistry in pharmaceutical compounds synthesis

Publication Name: Journal of Flow Chemistry
Publication Date: 2023-11-06
DOI: 10.1007/s41981-023-00285-x

New Developments in Microwave–Assisted Solid Phase Peptide Synthesis

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2020
DOI: 10.1007/978-1-0716-0227-0_6

Heterogeneous Catalysis

Publication Name: Science of Synthesis
Publication Date: 2017

Positional Scanning Substrate Combinatorial Library (PS-SCL) Approach to Define Caspase Substrate Specificity

Publication Name: Methods in molecular biology (Clifton, N.J.)
Publication Date: 2014
DOI: 10.1007/978-1-4939-0357-3_2